A.G.E. Interrupter Advanced

Anti-wrinkle cream

A.G.E. Interrupter Advanced is a potent corrective cream treatment that helps reverse visible signs ... Read full description

NEW BREAKTHROUGH

A.G.E. Interrupter Advanced

Anti-wrinkle cream

A.G.E. Interrupter Advanced Benefits

Visibly corrects a range of wrinkle types include fine lines, deep wrinkles and location-specific creases

Helps restore skin’s density, which is known to decline as glycation degrades skin’s collage

Visibly reduces discoloration for a healthier looking complexion

Complements collagen remodeling procedures, like RF microneedling

Helps reverse collagen glycation, a process known to visibly age skin, by 33%

Delivers rich all-day hydration, with a luxurious, satin finish

Free of parabens, drying alcohol, and dyes

Product Details

A.G.E. Interrupter Advanced is a potent corrective cream treatment that helps reverse visible signs of aging impacted by collagen decline and glycation, improving five types of wrinkles frequently targeted for aesthetic procedures.

SKIN TYPES: Dry, Normal, Combination, Sensitive

SKIN CONCERN: Aging

FEATURES:

This next-generation anti-wrinkle cream is formulated with 18% concentrated Proxylane (20% more than previous A.G.E. Interrupter), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. This advanced technology is clinically shown to help improve the appearance of five types of wrinkles frequently targeted for aesthetic procedures: forehead wrinkles, glabellar line, crow’s feet, nasolabial folds, and marionette lines.

*Due to the formula’s high levels of flavonoids, this cream's color may vary but will remain effective.

BENEFITS:

Helps reverse visible aging impacted by collagen decline & glycation
Reduces the appearance of five types of visible wrinkles targeted for aesthetic procedures: forehead wrinkles, glabellar lines (“11s”), crow’s feet, nasolabial folds (“smile lines”), and marionette lines
Smooths the appearance of both fine lines and deep wrinkles
Delivers rich, 24-hour hydration, with a luxurious, satin finish
Free of parabens, drying alcohol, and dyes

HOW TO USE >

SEE FAQS >

SCIENCE + PROOF

Visible Results

After 12 weeks, A.G.E. Interrupter Advanced improved
attributes associated with skin aging and glycation, including
lines and deep wrinkles in five facial zones.

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14%

Reduction in
global fine lines

11.5%

Reduction in
forehead wrinkles

11%

Reduction in
nasolabial folds

7%

Reduction in
marionette wrinkles

7%

Reduction in
glabellar wrinkles

7%

crow's feet lines

Visible Results

After 12 weeks, A.G.E. Interrupter Advanced improved attributes associated with skin aging and glycation, including lines and deep wrinkles in five facial zones.

11.5%

Reduction in forehead
wrinkles

14%

Reduction in global fine
lines

11%

Reduction in nasolabial
folds

7%

Reduction in marionette
wrinkles

7%

Reduction in glabellar
wrinkles

7%

Crow's feet lines

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The Science Behind

What is Skin Glycation?

Glycation is natural process that accelerates visible signs of aging. During the glycation process, excess sugars bind to skin-supporting proteins (like collagen and elastin) and form advanced glycation end-products (A.G.E.s). A.G.E.s weaken collagen, leading to wrinkles and laxity.

Signs of Glycation

Wrinkling and crepiness
Loss of firmness
Dull, sallow complexion

Glycation Dos and Don’ts

DO: Wear Sunscreen
Protect skin from UV damage and oxidative stress by applying broad-spectrum sunscreen daily.

DO: Reduce Sugar
Alcohol consumption and high-sugar diets can promote the glycation process.

DON’T: Expose Skin to Smoke
Cigarette smoke deposits a myriad of chemicals onto the skin in addition to speeding up the glycation process.

A.G.E. Interrupter Advanced + Skin Tightening Treatments

Protect your skin from A.G.E.s by integrating energy-based devices like radiofrequency or ultrasound treatments. Together, A.G.E. Interrupter Advanced and skin-tightening treatments can reverse the erosion of elasticity and firmness caused by glycation.

Key Ingredients

Paraben-Free

Dye-Free

Drying Alcohol-Free

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18% Concentrated Proxylane

Helps support skin’s integrity and correct visible signs of aging, like wrinkles and laxity.

4.25% Wild Fruit Flavonoids

Combination of blueberry and pomegranate extracts help reduce oxidative stresCB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.

1% Glycyrrhetinic Acid

Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

3% Hepes

Activates natural enzymes in skin to promote even cell turnover while hydrating skin.

1% Niacinamide

Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.

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How to Use A.G.E. Interrupter Advanced

1

Prep + Dispense

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest. With this potent formula, only a small amount is needed.

2

Apply + Complete

If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

Answers to your frequently asked
A.G.E. Interrupter Advanced questions.

How does A.G.E. Interrupter Advanced differ from the original A.G.E. Interrupter?

Like A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. A.G.E. Interrupter Advanced includes an increased concentration of Proxylane as well as additional efficacious ingredients in glycyrrhetinic acid HEPES that bring forth anti-glycation science and collagen decline reversal. The texture of A.G.E. Interrupter Advanced is the same as A.G.E. Interrupter, but the new formulation does have a different smell.

What does A.G.E. Interrupter Advanced do?

Can I use A.G.E. Interrupter Advanced with retinol?

Does A.G.E. Interrupter Advanced cream get rid of wrinkles?

What is glycation?

Glycation, a major factor of intrinsic and extrinsic aging, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.